ABSTRACT
The bioscaffold can be used in tissue engineering and regenerative medicine. The scaffolds used in tissue engineering must have high porosity to facilitate accelerated angiogenesis for feeding cells and repelling cell waste outside the scaffold. In this experimental study, we attempted to produce lung three-dimensional scaffold and assay its effect on cell penetration and migration. In an experimental study, rabbit lung tissue was decellularized and used as a scaffold for rabbit blastema cells. The scaffolds were studied on the 15[th] day after culturing. Microscopic features revealed high porosity in the lung tissue scaffold. Electron microscopic imaging also showed collagen and elastin were intact, which are important properties in scaffolds designed for tissue engineering. Migration and permeation of blastema cells into the lung tissue scaffold was also observed. Rabbit lung tissue scaffolds have high porosity. Blastema cells successfully migrated toward and permeated the scaffold inside
Subject(s)
Animals , Tissue Engineering , Tissue Scaffolds , RabbitsABSTRACT
A 16-years-old female patient with painless swelling of the right side of mandible is described. She noticed the swelling from two years ago, without painful symptoms. Axial CT imaging showed buccal expansion with intact buccal and lingual cortical bone. The report of incisional biopsy was central odontogenic fibroma. Under general anesthesia the lesion was removed after ostectomy of buccal cortical plate and inferior alveolar nerve preserved. Three-year follow-up after tumor excision relieved no recurrence
ABSTRACT
The calcifying odontogenic cyst [COC] is a rare odontogenic cyst. Only 2% of all odontogenic cysts and tumors are COC. COC associated with odontoma [COCaO] reported in 24% of COCs. COCaO presents a greater incidence in female, with a ratio of 2 to 1. The highest incidence of COCaO occurs during the second decade with a mean age of 16 years, most frequently occurring in the maxilla [61.5%]. Here, we describe a classic case of COCaO of the maxillary incisor-canine region in 17-year-old girl, and discuss the clinicopathological features and immunohistochemical finding of this tumor